Simon Labrie

Post-Doctoral Associate
Civil and Environmental Engineering
MIT 48-208
15 Vassar Street
Cambridge, MA 02139
Phone: (617) 253-8686
Fax: (617) 258-7009
Email: sjlabrie at mit.edu

Education:

2009
2002

 M.Sc./Ph.D in microbiology, Université Laval GREB
B.Sc. Microbiology, Université Laval, Québec, Canada

Research Interests:

I am mainly interested in bacteriophages biology. Phages in the environment are numerous and they are playing an important role in maintenance of the ecological balance. Despite the decades of research in that field, little is known about how these viruses interact with their host. Prochlorococcus and its phages is a unique phage/host system where the infection process requires the establishment of a complex interaction network. My research objective is to better understand the infection process; from the adsorption of the virus to the bacterial cell to the lysis.

Publications:

Labrie, S. J., J. Josephsen, H. Neve, F. K. Vogensen, and S. Moineau. 2008.
Morphology, genome sequence, and structural proteome of type phage P335 from
Lactococcus lactis.
Appl. Environ. Microbiol. 74:4636-44.

Labrie, S. J., and S. Moineau. 2007.
Abortive infection mechanisms and prophage sequences significantly influence the genetic makeup of emerging lytic lactococcal phages.
J. Bacteriol. 189: 1482-1487.

Deveau, H., S. J. Labrie, M.-C. Chopin, and S. Moineau. 2006.
Biodiversity and classification of lactococcal phages.
Appl. Environ. Microbiol. 72:4338-46.

Harel, J., G. Martinez, A. Nassar, H. Dezfulian, S. J. Labrie, R. Brousseau, S. Moineau, et M. Gottschalk. 2003.
Identification of an inducible bacteriophage in a virulent strain of Streptococcus suis serotype 2.
Infect. Immun. 71:6104-8.